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PC2118
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lianPC<span style="font-fam�� and surfactant properties have potential benefits in non-medical applications.
The following summarizes some examples of applicable features, benefits, and potential applications:
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Performance
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Advantages
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Potential application areas
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Reduce Protein attachment
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Reduce Scaling; easier to clean
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Food and beverage processing equipment; pharmaceutical processing equipment
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Reduce Use of high-intensity cleaning chemicals
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None Toxic marine anti-pollution
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Reduce Bacterial adhesion and biofilm formation
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Same as above , while reducing infection/pollution/Risk of spoilage
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Use Keep clean in the hospital/Easy-to-clean surface; water filtration system; latex
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Dear Water-based and moisturizing
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Enhance Moisturizing and conditioning
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Cosmetics ;Functional/Active textiles
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Delivery Active substances
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Active Materials and the above advantages
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Cosmetics ;Health products
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Application of PC Technology™ in Drug Delivery
In recent years, the development of drug-device combination products has brought about changes in some parts of the medical device field. Significant changes. Perhaps the most obvious example has always been the drug-eluting stents (DES) market, which has experienced explosive growth from $1.5 billion to $5 billion in two years. PC coating plays an important role in this field. Abbott’s PC dexamethasone stent, Dexamet®, the second DES to be marketed in Europe, and Medtronic’s PC-coated otralimus-eluting Endeavor® DES system, were notable in a two-year follow-up of 1,300 patients. During the trial, there was no case of late frame thrombosis. These application examples highlight the value of PC materials to the medical device market.
The flexible chemistry of PC polymers makes it possible to modify a variety of monomers, allowing the polymer to be tailored to different active substances and fine-tuning drug elution properties. Breakthrough drug-device combinations that demonstrate clinical benefits through controlled drug release, Ventrus’ expertise is well suited to serve the development and commercialization of combination products.
PC coating can:
o Adsorption of high molecular weight compounds
o Absorption of low molecular weight drugs
o Demonstrate precise drug content and controlled release
o Once the drug is released, it remains stable
PC coating can deliver:
o Anti-inflammatories o Analgesics
o Antibacterial drugs o Hormones
o DNA fragments used in gene therapy
Activities that have been studied Specific examples of substances:
o Dexamethasone o Estradiol
o Paclitaxel o Sirolimus
o Bamastat o Angiopep
o Dipyridamole
Manufacturer information
Headquarters and The Applications Laboratory is located in Hampshire, UK. The division is part of Vertruth Specialty Products UK Ltd., based in the north of England, and the company operates under an ISO9001:2008 quality management system certification (certificate number FM02222). Vertex Specialty Products UK Ltd has facilities to produce multi-tonne PC materials and has recently opened a new polymer chemistry R&D laboratory to support its biomaterials division operations. Ventrus is ideally suited to assist medical supply companies in applying the benefits of PC technology to address unmet clinical needs and provide value-added, differentiated products.
Perhaps the most obvious example has always been the drug-eluting stent (DES) market, which has experienced explosive growth from $1.5 billion to $5 billion in two years. PC coating plays an important role in this field. Abbott’s PC dexamethasone stent, Dexamet®, the second DES to be marketed in Europe, and Medtronic’s PC-coated otralimus-eluting Endeavor® DES system, were notable in a two-year follow-up of 1,300 patients. During the trial, there was no case of late frame thrombosis. These application examples highlight the value of PC materials to the medical device market.
The flexible chemistry of PC polymers makes it possible to modify a variety of monomers, allowing the polymer to be tailored to different active substances and fine-tuning drug elution properties. Breakthrough drug-device combinations that demonstrate clinical benefits through controlled drug release, Ventrus’ expertise is well suited to serve the development and commercialization of combination products.
PC coating can:
o Adsorption of high molecular weight compounds
o Absorption of low molecular weight drugs
o Demonstrate precise drug content and controlled release
o Once the drug is released, it remains stable
PC coating can deliver:
o Anti-inflammatories o Analgesics
o Antibacterial drugs o Hormones
o DNA fragments used in gene therapy
Activities that have been studied Specific examples of substances:
o Dexamethasone o Estradiol
o Paclitaxel o Sirolimus
o Bamastat o Angiopep
o Dipyridamole
Manufacturer information
Headquarters and The Applications Laboratory is located in Hampshire, UK. The division is part of Vertruth Specialty Products UK Ltd., based in the north of England, and the company operates under an ISO9001:2008 quality management system certification (certificate number FM02222). Vertex Specialty Products UK Ltd has facilities to produce multi-tonne PC materials and has recently opened a new polymer chemistry R&D laboratory to support its biomaterials division operations. Ventrus is ideally suited to assist medical supply companies in applying the benefits of PC technology to address unmet clinical needs and provide value-added, differentiated products.
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